临床输血与检验2017，Vol.19Issue(4)：340-342,3.DOI:10.3969/j.issn.1671-2587.2017.04.008
孕妇ABO血型系统以外不规则抗体致新生儿溶血病10例
Case Reports of N-ABO-Hemolytic Disease in Newborns Caused by Maternal Irregular Antibodies
摘要
Abstract
Objective To report 10 cases of N-ABO-hemolytic disease in newborns (N-ABO-HDN) caused by maternal irregular antibodies through retrospective analysis. Methods The NEO was used to detect the irregular antibodies,and the positive samples were further identified. Cord or venous blood were collected from 74 pregnant women with irregular antibodies for hemolytic disease of newborns after delivery. Results Seventy four of 23241 cases were found to present positive irregular antibodies. Among them,10 case of the survived infants were diagnosed as N-ABO-HDN. Two cases showed anti M-HDN; 3 cases,anti D –HDN; and 5 cases,anti E (anti Ec) -HDN. Conclusion Examination of irregular antibodies in pregnant women is quite usefull in ensuring the security of both mathers and foetuses. Early detection of irregular antibodies is crucial in multiparous pregnancies,especially in those with maternal habitual abortions.关键词
不规则抗体/孕妇/新生儿溶血病Key words
Irregular antibody/Maternal/Hemolytic Disease of Newborn(HDN)分类
医药卫生引用本文复制引用
王淑平,陈慧芬,李志强..孕妇ABO血型系统以外不规则抗体致新生儿溶血病10例[J].临床输血与检验,2017,19(4):340-342,3.基金项目
本课题受第四轮(2015-2017年)上海市公共卫生重点建设项目《输血医学》(No.15GWZK0501)资助 （2015-2017年）
