农药学学报2017，Vol.19Issue(4)：507-511,5.DOI:10.16801/j.issn.1008-7303.2017.0066
含苯并咪唑环的1,3,4-噻二唑酰胺衍生物的合成与抑菌活性
Synthesis and fungicidal activity of 1,3,4-thiadiazole amide derivatives containing benzimidazole moiety
摘要
Abstract
In order to discover novel heterocyclic compounds with biological activity, six novel 1,3,4-thiadiazole amide derivatives containing benzimidazole moiety were synthesized under microwave assisted condition via etherification, condensation, hydrocarbylation and the ammonolysis reactions with substituted phenol and chloracetic acid as raw materials. The structures were confirmed by IR and 1H NMR. Fungicidal activity test showed that all the compounds exhibit fungicidal activity against the five fungi tested at the concentration of 50 mg/L, among them, the inhibition rate of 7c, 7d, 7e and 7f against the fungi tested were above 80% .关键词
苯并咪唑/1,3,4-噻二唑/酰胺/抑菌活性Key words
benzimidazole/1/3/4-thiadiazole/amide/fungicidal activity分类
化学化工引用本文复制引用
郑广进,黄欢..含苯并咪唑环的1,3,4-噻二唑酰胺衍生物的合成与抑菌活性[J].农药学学报,2017,19(4):507-511,5.基金项目
2013 年度广西高校科学技术研究项目 (2013YB271). （2013YB271）
