实用妇产科杂志2017，Vol.33Issue(7)：512-516,5.
173例多胎妊娠选择性减胎术后的围生结局
Selective Fetal Reduction in Multiple Pregnancies:173 Cases in One Center
摘要
Abstract
Objective:To evaluate the perinatal outcome of multiple pregnancies after selective fetal reduction.Methods:173 cases of multiple pregnancies were performed selective reduction with transabdominal injection of potassium chloride(KCL) into fetal heart or radiofrequency ablation(RFA) in one single institution during January 2012 to September 2015.The clinical data was collected to review the perinatal outcome.Results:Transabdominal of KCL reduction was performed in 121 cases,the miscarriage rate was 10.0％ (11/110),while the survival rate was 89.2％.The miscarriage rate and ≤34 week preterm birth rate in the first trimester and the second trimester were no statistically significant differences(P ＞ 0.05).For reduction to singletons vs twins,the mean gestational age at delivery was 2 weeks longer in singletons (37.96 ± 2.65 vs 35.93 ± 2.19),and neonatal birth weights also greater(2.91 ±0.55 vs 2.51 ±0.44) (P＜0.05).Fifty-two cases of multiple pregnancies were performed RFA and the survival rate was 71.2％.Indications as TTTS,sFGR,TRAPs and structural or genetic abnormalities have different survival rate,which was 68.2％,83.3％,100.0％ and 53.8％,respectively.Conclusions:Transabdominal of KCL reduction can be performed in the first and second trimester,and the perinatal outcome seems more beneficial when reduced to singletons.The survival rate of sFGR and TRAPs was higher than other indications in RFA.Selective fetal reduction is beneficial for improving the prenatal outcome of multiple pregnancies.关键词
多胎妊娠/选择性/减胎/氯化钾减胎术/射频消融减胎术/结局Key words
Multiple pregnancy/Selective/Fetal reduction/Potassium chloride/Radiofrequency ablation/Pregnancy outcomes分类
医药卫生引用本文复制引用
王佳燕,李南,陈敏,潘悦健,李志华,翦薇,曹定娅,陈兢思,陈敦金..173例多胎妊娠选择性减胎术后的围生结局[J].实用妇产科杂志,2017,33(7):512-516,5.基金项目
广东省科技发展专项基金(编号:2016A030313610) （编号:2016A030313610）
