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厄贝沙坦联合胺碘酮对慢性心力衰竭患者P波离散度与阵发性心房颤动的影响

郑宏健 祝长芝

心脑血管病防治2017,Vol.17Issue(3):182-184,3.
心脑血管病防治2017,Vol.17Issue(3):182-184,3.DOI:10.3969/j.issn.1009-816x.2017.03.07

厄贝沙坦联合胺碘酮对慢性心力衰竭患者P波离散度与阵发性心房颤动的影响

Joint Effect of Irbesartan and Amiodarone on P Wave Dispersion and Paroxysmal Atrial Fibrillation in Patients with CHF

郑宏健 1祝长芝1

作者信息

  • 1. 272100 山东省济宁市第一人民医院心内科
  • 折叠

摘要

Abstract

Objective To explore joint effect of irbesartan and amiodarone on P wave dispersion and paroxysmal atrial fibrillation in patients with chronicheart failure (CHF).Methods 90 patients with CHF of our hospital in May 2014 were selected and randomly divided into control group and observation group,with 45 cases in each group.Both groups were given basic treatment of CHF at first.Then the control group was treated with irbesartan while the observation group was treated with amiodarone.After 6 months of therapy,the change of P wave dispersion and paroxysmal atrial fibrillation were compared between the two groups.Results Compared with before treatment,P wave maximum and P wave dispersion decreased in both groups after treatmem,but the above indexes improved more significantly in the observation group than those in the control group (P < 0.05).After the treatment,LVDd was reduced while LVEF was increased in two groups.These improvements were more significantly in the observation group (P < 0.05).The incidence of atrial fibrillation was decreased in the two groups after the treatment,but the observation group improved more significantly than the other group (P < 0.05).Conclusions Combined with amiodarone,irbesartan is able to reduce p wave dispersion and the frequency of atrial fibrillation as well as reverse left ventricular hypertrophy in the treatment of CHF.

关键词

厄贝沙坦/胺碘酮/慢性心力衰竭/P波离散度/阵发性心房颤动

Key words

Irbesartan/Amiodarone/Congestive hearts failure/P wave dispersion degree/Paroxysmal atrial fibrillation

分类

医药卫生

引用本文复制引用

郑宏健,祝长芝..厄贝沙坦联合胺碘酮对慢性心力衰竭患者P波离散度与阵发性心房颤动的影响[J].心脑血管病防治,2017,17(3):182-184,3.

心脑血管病防治

OACSTPCD

1009-816X

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