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核磁共振技术及定量核磁共振技术在毒品分析中的应用

李彭 赵阳 赵彦彪 杨虹贤 高利生

刑事技术2017,Vol.42Issue(4):312-323,12.
刑事技术2017,Vol.42Issue(4):312-323,12.DOI:10.16467/j.1008-3650.2017.04.011

核磁共振技术及定量核磁共振技术在毒品分析中的应用

NMR and qNMR for Drug Analysis

李彭 1赵阳 1赵彦彪 1杨虹贤 1高利生1

作者信息

  • 1. 公安部物证鉴定中心,北京 100038
  • 折叠

摘要

Abstract

This review is based on the literature published between 2006 and now. The methodology of NMR (nuclear magnetic resonance), in particular qNMR (quantitative NMR), was selected because of the need for the examination and quantitative analysis of controlled drugs and new psychoactive substances. NMR with external calibration is unique in its discriminative function. Experimenters may never need identical reference materials because NMR provides formidable precision and accuracy when properly handled, capable of leading towards simultaneous detection of multiple substances. New generations of cathinone and cannabinoid products are constantly emerging into market. As a result, it has become urgent for forensic laboratories to be able to promptly detect and identify synthetic cannabinoids in their original powder forms and/or other consumable products, with minimal sample preparation and clean-up steps. At present, the major challenge is the lack of both available analytical research information on these substances and reference standards, since these drugs are new to the market and forensic community and consequently have not yet been characterized. There is a critical demand for the analytical characterization of these psychoactive substances to facilitate their detection and thereby prevent their abuse. Coincidently, NMR and qNMR provide the capability to meet the demand.

关键词

核磁共振/定量核磁共振/毒品/精神活性物质

Key words

NMR (nuclear magnetic resonance)/qNMR (quantitative NMR)/drugs/psychoactive substances

分类

社会科学

引用本文复制引用

李彭,赵阳,赵彦彪,杨虹贤,高利生..核磁共振技术及定量核磁共振技术在毒品分析中的应用[J].刑事技术,2017,42(4):312-323,12.

基金项目

Basic Research Program Exclusive for Central Government-class Institutes of Public Welfare (No. 2016JB008) (No. 2016JB008)

刑事技术

OACSTPCD

1008-3650

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