刑事技术2017,Vol.42Issue(4):312-323,12.DOI:10.16467/j.1008-3650.2017.04.011
核磁共振技术及定量核磁共振技术在毒品分析中的应用
NMR and qNMR for Drug Analysis
摘要
Abstract
This review is based on the literature published between 2006 and now. The methodology of NMR (nuclear magnetic resonance), in particular qNMR (quantitative NMR), was selected because of the need for the examination and quantitative analysis of controlled drugs and new psychoactive substances. NMR with external calibration is unique in its discriminative function. Experimenters may never need identical reference materials because NMR provides formidable precision and accuracy when properly handled, capable of leading towards simultaneous detection of multiple substances. New generations of cathinone and cannabinoid products are constantly emerging into market. As a result, it has become urgent for forensic laboratories to be able to promptly detect and identify synthetic cannabinoids in their original powder forms and/or other consumable products, with minimal sample preparation and clean-up steps. At present, the major challenge is the lack of both available analytical research information on these substances and reference standards, since these drugs are new to the market and forensic community and consequently have not yet been characterized. There is a critical demand for the analytical characterization of these psychoactive substances to facilitate their detection and thereby prevent their abuse. Coincidently, NMR and qNMR provide the capability to meet the demand.关键词
核磁共振/定量核磁共振/毒品/精神活性物质Key words
NMR (nuclear magnetic resonance)/qNMR (quantitative NMR)/drugs/psychoactive substances分类
社会科学引用本文复制引用
李彭,赵阳,赵彦彪,杨虹贤,高利生..核磁共振技术及定量核磁共振技术在毒品分析中的应用[J].刑事技术,2017,42(4):312-323,12.基金项目
Basic Research Program Exclusive for Central Government-class Institutes of Public Welfare (No. 2016JB008) (No. 2016JB008)