针刺研究2017，Vol.42Issue(4)：342-345,4.DOI:10.13702/j.1000-0607.2017.04.011
针刺十三鬼穴对肝性脑病患者肝功能、血氨及β-内啡肽水平的影响
Effect of Acupuncture at Thirteen Evil Acupoints on Liver Function, and the Contents of Blood Ammonia and β-endorphin in Patients with Hepatic Encephalopathy
苏红慧 1崔厚松 2苏会玲3
作者信息
- 1. 华北石油管理局总医院药材科,河北沧州 062552
- 2. 河北省衡水市故城县医院中医内科,河北衡水 253800
- 3. 华北石油管理局总医院肿瘤科,河北沧州 062552
- 折叠
摘要
Abstract
Objective To observe the therapeutic effect of acupuncture at thirteen evil acupoints in patients with hepatic encephalopathy, and to explore its possible mechanism.Methods Patients with hepatic encephalopathy were randomly divided into acupuncture group (n=38) and western medicine group (n=36).Patients in the western medicine group were treated by intravenous injection of aspartate ornithine and branched chain amino acids, and those in the acupuncture group were treated with acupuncture at thirteen evil acupoints on the basis of the western medicine.All the patients were treated for 1 week.The liver function and blood ammonia were measured by automatic biochemical analyzer.The changes of plasma β-endorphin were measured by enzyme-linked immunosorbent assay (ELISA).Results Following the treatment, of the 36 and 38 hepatic encep-halopathy patients in the western medicine and acupuncture groups, 12 and 18 experienced a marked improvement in their symptoms, 13 and 16 were effective, and 11 and 4 invalid, with the effective rates being 69.4% and 89.5%, respectively.Compared with pre-treatment, the levels of serum aspartate aminotransferase, alanine aminotransferase, total bilirubin, and plasma β-endo-rphin and blood ammonia were significantly lower in both western medicine and acupuncture groups(P<0.01), and the therapeutic effects of the acupuncture group were obviously superior to those of the western medicine group in the above mentioned indexes (P<0.05, P<0.01).Conclusion Treatment of acupuncture at thirteen evil acupoints combined with western medicine can enhance the curative effect of hepatic encephalopathy, improve patients'' liver function and decrease the levels of plasma ammonia and β-endorphin.关键词
针刺/十三鬼穴/肝性脑病/血氨/β-内啡肽Key words
Acupuncture/Thirteen evil acupoints/Hepatic encephalopathy/Blood ammonia/β-endorphin分类
医药卫生引用本文复制引用
苏红慧,崔厚松,苏会玲..针刺十三鬼穴对肝性脑病患者肝功能、血氨及β-内啡肽水平的影响[J].针刺研究,2017,42(4):342-345,4.
