针刺研究2017,Vol.42Issue(4):350-353,4.DOI:10.13702/j.1000-0607.2017.04.013
腹针结合温针灸治疗膝关节骨性关节炎临床研究
Clinical Studies of Abdominal Acupuncture Combined with Warm Needling on Knee Osteoarthritis
摘要
Abstract
Objective To explore the clinical effects of abdominal acupuncture combined with warm needling on knee osteoarthritis (KOA).Methods Eighty-six patients with KOA were divided into a treatment group and a control group according to the digital random table, 43 cases in each one.In the treatment group, patients were treated with abdominal acupuncture at Zhongwan (CV 12), Guanyuan (CV 4) and Huaroumen (ST 24), Wailing (ST 26) and Xiafengshidian (Extra) on the affected side, as well as warm needling at Neixiyan (EX-LE 4), Dubi (ST 35), Heding (EX-LE 2), Liangqiu (ST 34) and Xuehai (SP 10) of the affected side.In the control group, warm needling was given.All the patients were treated 5 times a week for 4 weeks.Each dimension score of Western Ontario and McMaster University (WOMAC) osteoarthritis index scale and health survey 36-item short form (SF-36) of the two groups was compared before and after treatment.Enzyme-linked immunosorbent assay was applied to test serum vascular endothelial growth factor (VEGF) and angiopoietin-1(Ang-1).Results Compared with those before treatment, the scores of pain, stiffness, joint function of WOMAC scale and serum VEGF, Ang-1 of the two groups were lower after treatment (all P<0.01), and each dimension score of SF-36 scale increased significantly (all P<0.01).Each dimension score of WOMAC scale and serum VEGF, Ang-1 in the treatment group were lower than those in the control group after treatment (all P<0.01), and each score of SF-36 was higher (all P<0.01).The total effective rate of 93.0% (40/43) in the treatment group was higher than 74.4% (32/43) in the control group (P<0.05).Conclusion Abdominal acupuncture combined with warm needling can effectively alleviate pain and stiffness, improve the function of knee joint and quality of life, with definite effect for KOA.The mechanism may be related to the decreasing of serum VEGF and Ang-1.关键词
膝关节骨性关节炎/腹针/温针灸Key words
Knee osteoarthritis/Abdominal acupuncture/Warm needling分类
医药卫生引用本文复制引用
李其友,郭瑾,田华张,张春燕,彭志贤,黄兴鹏..腹针结合温针灸治疗膝关节骨性关节炎临床研究[J].针刺研究,2017,42(4):350-353,4.基金项目
广东省深圳市宝安区科技计划项目(No.2015290) (No.2015290)