中国动脉硬化杂志2017，Vol.25Issue(8)：830-834,5.
脑卒中高危人群幽门螺杆菌感染对AIP、血脂异常的影响
Effect of helicobacter pylori infection on AIP and dyslipidemia in patients with high risk of stroke
王龙 1赵学敏 1袁肖征 1胡中文 1余勇 1邓奇 1王复郁2
作者信息
- 1. 皖北煤电集团总医院蚌埠医学院第三附属医院神经内科,安徽省宿州市234000
- 2. 皖北煤电集团总医院蚌埠医学院第三附属医院药剂科,安徽省宿州市234000
- 折叠
摘要
Abstract
Aim To investigate the relationship among helicobacter pylori (Hp) infection with blood lipid level and AIP in patients with high risk of stroke,and to provide new ideas for the treatment of dyslipidemia and atherosclerosis.Methods Three hundred and sevety-one patients with high risk of stroke were screened from 2872 people who were consecutively selected and had health examination from June 2014 to January 2015 in the Department of Medical Center,General Hospital of Wanbei Coal and Electricity Group.Their clinical information was collected.The Hp infection status was detected by the 14C urea breath test and the serum oxidized low density lipoprotein (ox-LDL) levels was determined by enzyme linked immunesorb-ent assay (ELISA).The relationship between Hp infection and total cholesterol (TG),triglyceride (TG),low density lipoprotein (LDLC),high density lipoprotein (HDLC),ox-LDL,AIP were analyzed.Results 155 patients(41.8％,155/371)were found infected by Hp;the levels of TC,TG,LDLC,ox-LDL and AIP in Hp infection group were significandy higher than those in non HP infection group,the difference was statistically significant (P＜0.05).Multiple linear regression analysis showed that Hp infection was positively correlated with the level of AIP.Conclusion Hp infection may induce the disorder of lipid metabolism in high risk population of cerebral apoplexy,which leads to the increase of AIP level,and promotes the development of atherosclerosis.关键词
脑卒中/幽门螺杆菌/血脂异常/促动脉硬化指数/动脉粥样硬化Key words
Stroke/Helicobacter pylori/Dyslipidemias/AIP/Atherosclerosis分类
医药卫生引用本文复制引用
王龙,赵学敏,袁肖征,胡中文,余勇,邓奇,王复郁..脑卒中高危人群幽门螺杆菌感染对AIP、血脂异常的影响[J].中国动脉硬化杂志,2017,25(8):830-834,5.
