中国免疫学杂志2017，Vol.33Issue(8)：1228-1231,1235,5.DOI:10.3969/j.issn.1000-484X.2017.08.022
ADSCs干预治疗创伤性股骨颈骨折的可行性探讨
Feasibility study of adipose-derived mesenchymal stem cells in repairing traum-atic femoral neck fracture
摘要
Abstract
Objective:To explore the feasibility of ADSCs in the clinical treatment of traumatic femoral neck fracture.Methods: After the intervention by ADSCs,femoral neck fracture repair was observed by hematoxylin-eosin staining.The vascular endothelial growth factor expression levels at the fracture segment were quantitatively measured by immunohistochemical staining,RT-qPCR was utilized to detect the mRNA formation in callus tissue.Results: In the study group,we observed less fracture repair than in the sham surgery group but more than in the blank group.Conclusion: ADSCs administration can promote osseous tissue and osteoblast repair,thereby contributing to the healing of traumatic femoral neck fracture in rats.关键词
ADSCs/创伤性股骨颈骨折/VEGFKey words
ADSCs/Traumatic femoral neck fracture/VEGF分类
医药卫生引用本文复制引用
秦朝,司艳莉,官立萍,郭伟..ADSCs干预治疗创伤性股骨颈骨折的可行性探讨[J].中国免疫学杂志,2017,33(8):1228-1231,1235,5.基金项目
本文受2016年河南省高等学校重点科研项目(16A610012)和2017年河南省科技攻关计划项目(172102210449)资助. （16A610012）
