中国医学装备2017,Vol.14Issue(8):50-52,3.DOI:10.3969/J.ISSN.1672-8270.2017.08.014
ICU患者下呼吸道感染耐甲氧西林金黄色葡萄球菌耐药性分析
A drug resistance analysis for MRSA infecting lower respiratory tract of patient in
ICU
赵文申 1林丽萍 2崔庆庆 1时东彦3
作者信息
- 1. 邯郸市中心医院检验科 河北 邯郸 056001
- 2. 邯郸市中心医院感染管理科 河北 邯郸 056001
- 3. 河北医科大学第二医院检验科 河北 石家庄 050000
- 折叠
摘要
Abstract
Objective:To investigate the isolation rate and drug resistance of methicillin resistant staphylococcus aureus (MRSA) from sputum sample of patients with infection in lower respiratory tract of intensive care unit (ICU) so as to guide the reasonable using of antibiotic in clinical practice.Methods: Sputum samples of 506 patients with lower respiratory tract infection of ICU were collected and then they were implemented bacteria culture, identification and drug sensitivity experiment. The results of identification and drug sensitivity were analyzed and the characteristics of drug resistance were analyzed and discussed.Results: There were 79 strains staphylococcus aureus included 71 strains MRSA were isolated from the sputum samples of 506 patients. The sensitivity rates of isolated MRSA were 100% for vancomycin, teicoplanin and linezolid. At the same time, it was whole drug resistance for oxacillin and penicillin. The difference for rifampicin between MRSA and methicillin susceptible staphylococcus aureus (MSSA) was significant (x2=30.15,P<0.05).Conclusion: The therapeutic schedule of individualization and rationalization should be formulated according to the result of drug sensitivity and the characteristics of drug resistance of patient so as to efficiently reduce and prevent the infection and prevalence of MRSA.关键词
重症监护室/耐甲氧西林金黄色葡萄球菌/耐药性Key words
Intensive care unit/Methicillin-resistant staphylococcus aureus (MRSA)/Resistance分类
医药卫生引用本文复制引用
赵文申,林丽萍,崔庆庆,时东彦..ICU患者下呼吸道感染耐甲氧西林金黄色葡萄球菌耐药性分析[J].中国医学装备,2017,14(8):50-52,3.