中国药业2017,Vol.26Issue(15):10-12,3.DOI:10.3969/j.issn.1006-4931.2017.15.003
莲芝消炎胶囊一步制粒工艺研究
One-Step Granulation Process for Lianzhi Xiaoyan Capsule
郑如文 1胡卫林 1杨建锐 1程国华2
作者信息
- 1. 广州白云山光华制药股份有限公司,广东广州 510285
- 2. 暨南大学药学院,广东广州 510632
- 折叠
摘要
Abstract
Objective To establish a one-step granulation process for Lianzhi Xiaoyan Capsule. Methods To select the optimum one-step granulation process for Lianzhi Xiaoyan Capsule, the adhesive concentration, adhesive dosage and spray frequency for the process were optimized by orthogonal test with the granulating and filling condition as evaluation indexs. Results It was the optimum process:3% starch slurry for the adhesive concentration , 2. 2 kg for the adhesive dosage and 120 g / min for the spray frequency . Conclusion With one-step granlation process, the heating time is shorted, the process is much simpler, which can be used for the production of Lianzhi Xiaoyan Capsule of further promotion.关键词
莲芝消炎胶囊/一步制粒工艺/正交试验Key words
Lianzhi Xiaoyan Capsule/one-step granulation process/orthogonal test分类
化学化工引用本文复制引用
郑如文,胡卫林,杨建锐,程国华..莲芝消炎胶囊一步制粒工艺研究[J].中国药业,2017,26(15):10-12,3.