中国药业2017，Vol.26Issue(15)：16-19,4.DOI:10.3969/j.issn.1006-4931.2017.15.005
复方益母胶囊质量标准提高研究
Improvement of the Quality Standard of Fufang Yimu Capsule
李柯 1陈丹 2李若存 1蒋波 1林凡友 3王文天3
作者信息
- 1. 湖南省中医药研究院,湖南长沙 410013
- 2. 湘潭医卫职业技术学院,湖南湘潭 411102
- 3. 翔宇药业股份有限公司,山东临沂 276023
- 折叠
摘要
Abstract
Objective To improve the quality control standard of Fufang Yimu Capsule. Methods TLC was used for identification of Leonuri Herba in Fufang Yimu Capsule. HPLC was used for quantitative analysis. The Hypersil NH2 column ( 250 mm × 4. 6 mm,5 μm ) was used with the mobile phase of mixture of phosphate buffer-acetonitrile ( pH=5. 5, 20:80 ) , the detection wavelength was 192 nm. Results TLC sports developed were fairy clear, and the blank test showed no interference. The linear relationship of stachydrine hydrochlo-ride was good in the range of 0. 027-0. 162 g/L ( r=0. 9995 ) . The average recovery rate was 97. 58%, RSD=2. 82%(n=9). Conclusion The established qualitative and quantitative analysis method is applicable for the quality control of Fufang Yimu Capsule.关键词
复方益母胶囊/质量标准/高效液相色谱法/盐酸水苏碱Key words
Fufang Yimu Capsule/quality standard/HPLC/stachydrine hydrochloride分类
医药卫生引用本文复制引用
李柯,陈丹,李若存,蒋波,林凡友,王文天..复方益母胶囊质量标准提高研究[J].中国药业,2017,26(15):16-19,4.
