摘要
Abstract
Objective To investigate the clinical efficacy and safety of levofloxacin in the treatment of multi-drug resistant pulmonary tuberculosis. Methods Totally 85 patients with multi-drug resistant pulmonary tuberculosis admitted to the hospital from June 2014 to June 2016 were divided into two groups according to the different treatment methods. The control group ( n=40 ) was given conventional chemotherapy, the observation group ( n=45 ) was given levofloxacin based on the conventional chemotherapy treatment. The therapeutic effects of the two groups were compared. Results The effective rate in the observation group was 95. 56%, which was significantly higher than 62. 50% in the control group (χ2=14. 462, P < 0. 05 ) . The absorption rate of lesion was 88. 89%, which was significantly higher than 62. 50% of the control group (χ2=8. 196, P < 0. 05 ) . The incidence rate of adverse reactions in the observation group was 13. 33% , which was significantly lower than 32. 50% in the control group (χ2=4. 482, P < 0. 05 ) . Conclusion The effect of lev-ofloxacin in the treatment of multi-drug resistant pulmonary tuberculosis is remarkable, it can effectively reduce the incidence of ad-verse reactions, which is worthy of clinical promotion.关键词
左氧氟沙星/耐多药肺结核/疗效/药品不良反应Key words
levofloxacin/multi-drug resistant pulmonary tuberculosis/curative effect/adverse drug reaction分类
医药卫生
