中国药业2017，Vol.26Issue(15)：76-78,3.DOI:10.3969/j.issn.1006-4931.2017.15.027
利奈唑胺治疗革兰阳性球菌重症感染的疗效和安全性评价
Efficacy and Safety of Linezolid in Treating Severe Infection of Gram Positive Coccus
李雪锋1
作者信息
- 1. 四川省眉山市人民医院,四川眉山 620010
- 折叠
摘要
Abstract
Objective To observe the efficacy and safety of linezolid in the treatment of severe infection of gram positive coccus. Methods Totally 86 patients with severe infection from gram positive coccus admitted to our hospital from October 2014 to October 2016 were selected and divided into the observation group and the control group according to the odd and even number method, 43 cases in each group. The control group was treated with vancomycin, and the observation group was treated with linezolid. Results The onset time and length of hospital stay in the observation group were shorter than those in the control group ( P < 0. 05 ) . The clearance rate of gram-positive coccus in the observation group was 93. 02%, which was significantly higher than 72. 09% in the control group ( P < 0. 05 ) . The incidence rate of adverse reactions in the observation group was 6. 98%, which was lower than 23. 26% in the control group ( P < 0. 05 ) . Conclusion The efficacy and safety of linezolid in the treatment of severe infection of gram positive coccus are good, it is worthy of clinical promotion.关键词
万古霉素/革兰阳性球菌/重症感染/利奈唑胺/疗效Key words
vancomycin/gram positive coccus/severe infection/linezolid/curative effect分类
医药卫生引用本文复制引用
李雪锋..利奈唑胺治疗革兰阳性球菌重症感染的疗效和安全性评价[J].中国药业,2017,26(15):76-78,3.
