摘要
Abstract
Objective To investigate the clinical efficacy of piperacillin combined fish oil emulsion in the treatment of severe hospital acquired pneumonia. Methods Totally 128 patients with severe hospital acquired pneumonia from 2012 to 2015 were selected and randomly divided into the treatment group and the control group,64 cases in each group. The control group received intravenous infusion of piperacillin,on this basis,the treatment group was given intravenous infusion of fish oil emulsion. After 14 d of treatment,the clinical efficacy between the two groups was compared,the CRP,PaO2/FiO2,time of mechanical ventilation,time of antibiotics usage,rate of bacterial clearance and level of inflammatory factors were detected before and after treatment,and the incidence of adverse reactions was recorded. Results After 14 d of treatment,the total effective rate in treatment group was 78. 12%,which was significantly higher than 56. 25% in control group( P < 0. 05). The observed indexes and levels of inflammatory factors in the two groups were significantly better than those before treatment,and the treatment group was significantly improved than the control group( P < 0. 05). The incidence rates of adverse reactions were very low in the two groups( P > 0. 05). Conclusion Piperacillin combined fish oil emulsion in the treatment of severe hospital acquired pneumonia has good effect and short course of treatment with fewer adverse reactions,which is worthy of clinical promotion.关键词
哌拉西林/鱼油脂肪乳剂/医院获得性肺炎/临床疗效Key words
piperacillin/fish oil emulsion/hospital acquired pneumonia/clinical effect分类
医药卫生
