摘要
Abstract
Objective To investigate the clinical effect of octreotide in the treatment of liver cirrhosis complicated with upper gastroin-testinal hemorrhage(UGIH). Methods Totally 90 patients with liver cirrhosis complicated with UGIH in our hospital from June 2014 to June 2016 were randomly divided into the control group and the observation group,45 cases in each group. The control group was given pituitrin,while the observation group was given octreotide. Results The total effective rate of the observation group was 91. 11%,which was significantly higher than 75. 56% of the control group(χ2=3. 92,P < 0. 05). The Child-Pugh score,albumin,hemoglobin,prothrombin time(PT)between the two groups were statistically significant difference( t=4. 19,2. 16,3. 14,7. 69,P < 0. 05). The average hemostasis time of the observation group was (22. 4 ± 12. 8) h,which were significantly shorter than (35. 9 ± 15. 4) h in the control group( t=4. 52,P < 0. 05). The incidence rate of adverse reactions in the observation group was 8. 89%,which was significantly lower than 26. 67% in the control group(χ2=4. 86,P < 0. 05). Conclusion Octreotide in the treatment of liver cirrhosis combined with UGIH has good effect and safety,it is worthy of clinical promotion.关键词
奥曲肽/垂体后叶素/肝硬化/上消化道出血/临床疗效Key words
octreotide/pituitrin/hepatocirrhosis/upper gastrointestinal hemorrhage/clinical effect分类
医药卫生
