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c-TCD阳性的隐源性卒中的临床及影像学特点

段景怡 陈蓓蓓

中国卒中杂志2017,Vol.12Issue(8):686-690,5.
中国卒中杂志2017,Vol.12Issue(8):686-690,5.DOI:10.3969/j.issn.1673-5765.2017.08.006

c-TCD阳性的隐源性卒中的临床及影像学特点

Clinical and Imaging Features of c-TCD Positive Cryptogenic Stroke

段景怡 1陈蓓蓓2

作者信息

  • 1. 721000 宝鸡 宝鸡市中医医院脑病科
  • 2. 西京医院神经内科
  • 折叠

摘要

Abstract

Objective To analyze the clinic features and radiologic characteristics of cryptogenic stroke patients with positive contrast-enhanced transcranial Doppler (c-TCD) examination. Methods Subjects diagnosed as cryptogenic stroke by TOAST subtypes were recruited consecutively from patients who were hospitalized in our hospital between January 2013 and December 2016. Subjects were divided into two groups: c-TCD positive group (with right to left shunt) and c-TCD negative group(without right to left shunt). Demographic characteristics, common risk factors of cerebrovascular disease, radiologic features of infarct focus were analyzed and compared. Results A total of 113 subjects were enrolled, including 60 ones in c-TCD positive group and 53 ones in c-TCD negative group. Using transesophageal echocardiography (TEE) and computed tomography (CT) pulmonary angiography, 52 in c-TCD positive group were diagnosed with patent foramen ovale (PFO), and 1 was diagnosed with atrial septal defect. Compared to the c-TCD positive group, the negative group was older (P<0.05), and had more risk factors including blood hypertension, high hypercholesteremia, and smoking (P<0.05). The difference of cases with no traditional risk factors between c-TCD positive and negative groups was significant (P<0.01). The two groups showed no significant difference in responsible vessels (P>0.05). Infarct foci in c-TCD positive group were more likely to be in cortical or subcortical area (P=0.004), while in negative group, they were more likely to be in deep grey matter (P=0.015). Conclusion Cryptogenic stroke patients with c-TCD positive tended to be younger, with less traditional risk factors (blood hypertension, high hypercholesteremia and smoking). There were no significant differences in responsible vessels between c-TCD positive and negative groups. Infarct foci in c-TCD positive group were more likely to be in cortical or subcortical area.

关键词

TCD发泡试验/隐源性卒中/卵圆孔未闭

Key words

Contrast-enhanced transcranial Doppler/Cryptogenic stroke/Patent foramen ovale

引用本文复制引用

段景怡,陈蓓蓓..c-TCD阳性的隐源性卒中的临床及影像学特点[J].中国卒中杂志,2017,12(8):686-690,5.

中国卒中杂志

OACSTPCD

1673-5765

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