中国卒中杂志2017，Vol.12Issue(8)：759-764,6.DOI:10.3969/j.issn.1673-5765.2017.08.024
脑微出血发病机制、流行病学、影像学表现及其临床意义
Pathogenesis, Epidemiology, Imaging Manifestations and Clinical Significance of Cerebral Microbleeds
摘要
Abstract
Cerebral microbleeds (CMBs) belong to the category of cerebral small vessel disease (CSVD). The pathogenesis, risk factors and clinical significance of different types of CSVD are different. Many studies have shown that CMBs had become the important risk factors for influencing post-stroke hemorrhagic transformation, prognosis and recurrence, and causing cognitive impairment and loss of age-related ability. CMBs was closely associated with intracerebral hemorrhage, which could be used as some prediction indicators of the auxiliary diagnosis of cerebral vascular disease and bleeding. Further meticulous research on them can help to reveal the mechanism of CSVD, and have important guiding significance for thrombolysis, anticoagulant, antiplatelet and other treatment programs. Therefore, to explore the pathogenesis of CMBs (including genetic genetics, histopathology), early warning and intervention means is the key to solve the above-mentioned medical problems. In this paper, the definition and controversy, pathogenesis, epidemiology, imaging manifestations and clinical significance of CMBs were reviewed and the prospect of the research was also raised so as to provide enlightment for CMBs related studies.关键词
脑微出血/磁敏感加权成像/脑小血管病/发病机制Key words
Cerebral microbleeds/Susceptibility-weighted imaging/Cerebral small vessel diseases/Pathogenesis引用本文复制引用
于永鹏,谭兰..脑微出血发病机制、流行病学、影像学表现及其临床意义[J].中国卒中杂志,2017,12(8):759-764,6.基金项目
国家自然科学基金(81400957) （81400957）
