川北医学院学报2017，Vol.32Issue(4)：483-487,5.DOI:10.3969/j.issn.1005-3697.2017.04.001
聚醚醚酮/碳纳米管/生物活性玻璃复合材料的成骨细胞相容性研究
Study on osteoblast compatibility of polyetheretherketone/carbon nanotubes/bioactive glasses composite
摘要
Abstract
Objective:To explore osteoblast compatibility of polyetheretherketone/carbon nanotubes/bioactive glasses (PEEK/CNTs/BGs) composite in vitro.Methods:PEEK/CNTs/BGs composite was co-cultured with osteoblast MC3T3-E1 in vitro to evaluate the effects of the composite on osteoblast proliferation by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltet razolium bromide (MTT) and acridine orange fluorescent staining method.Meanwhile,the adhesion and growth of MC3T3-E1 cells on PEEK/CNTs/BGs composite surface were observed by scanning electron microscopy (SEM).Results:It was found that MC3T3-E1 cells on PEEK/CNTs/BGs composite surface had better proliferation activity than that on PEEK and polyetheretherketone/carbon nanotubes (PEEK/CNTs) composite surfaces.SEM results showed that PEEK/CNTs/BGs composite surface was conductive to MC3T3-E1 cells adhesion,spreading and growth.Conclusion:PEEK/CNTs/BGs composite has excellent osteoblast compatibility in vitro and might be used as a novel orthopedic material.关键词
聚醚醚酮/碳纳米管/生物活性玻璃/成骨细胞相容性/骨科材料Key words
Polyetheretherketone/Carbon nanotubes/Bioactive glasses/Osteoblast compatibility/Orthopedic material分类
医药卫生引用本文复制引用
郑延延,刘吕花,韩崇涛,熊成东,张丽芳..聚醚醚酮/碳纳米管/生物活性玻璃复合材料的成骨细胞相容性研究[J].川北医学院学报,2017,32(4):483-487,5.基金项目
中国科学院"西部之光"重点项目 （）
川北医学院博士基金项目(CBY16-QD-02) （CBY16-QD-02）
川北医学院科研发展计划项目(CBY16-A-ZD02) （CBY16-A-ZD02）
