川北医学院学报2017，Vol.32Issue(4)：638-642,5.DOI:10.3969/j.issn.1005-3697.2017.04.044
乳腺癌与Bcl-2、Caspase-3的相关性研究与应用
The relevant research and application between Bcl-2 and Caspase-3 with breast cancer
摘要
Abstract
Breast cancer is one of the most common malignant tumors in women.The incidence of breast cancer has been increasing year by year.In recent years,the cell apoptosis has been paid more attention in the development of breast cancer.Bcl-2 is the anti-apoptotic gene,which can inhibit cell apoptosis and prolong cell life.Caspase-3 is the most important central molecule and the executor of apoptosis,which can degrade a variety of substrate proteins,and lead to cell apoptosis.Bcl-2 and Caspase-3 are closely associated with the pathogenesis of breast cancer.But there are significant differences about the expression of Bcl-2 and Caspase-3 in breast cancer.In addition,it is a controversial issue that the relationship between Bcl-2 and Caspase-3 with the clinicopathological characteristics of breast cancer and the prognosis of breast cancer patients,which need for further study.关键词
乳腺癌/细胞凋亡/Bcl-2/Caspase-3Key words
Breast cancer/Cell apoptosis/Bcl-2/Caspase-3分类
医药卫生引用本文复制引用
刘斌,游金辉..乳腺癌与Bcl-2、Caspase-3的相关性研究与应用[J].川北医学院学报,2017,32(4):638-642,5.基金项目
2014年南充市应用技术研究与开发资金项目(14A0041) （14A0041）
