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丹归消肿膏外敷对大鼠急性软组织损伤的消肿止痛作用

杨大伟 宋雪 罗宗键 冷向阳

长春中医药大学学报2017,Vol.33Issue(4):536-538,3.
长春中医药大学学报2017,Vol.33Issue(4):536-538,3.DOI:10.13463/j.cnki.cczyy.2017.04.007

丹归消肿膏外敷对大鼠急性软组织损伤的消肿止痛作用

Effect of Dangui Xiaozhong ointment on acute soft tissue injury in rat models

杨大伟 1宋雪 1罗宗键 2冷向阳2

作者信息

  • 1. 中国中医科学院广安门医院南区骨二科,北京 102600
  • 2. 长春中医药大学附属医院骨科,长春 130021
  • 折叠

摘要

Abstract

Objective To observe the effect of external using Dangui Xiaozhong ointment in treating acute soft tissue injury (ASTI) in rat models. Methods 36 Wistar rats were randomly divided into model group (A), Liaoyuan Qilisan group (B) and Dangui Xiaozhong ointment group (C). Group A rats were coated with matrix ointment, B group was coated with Liaoyuan Qilisan and group C was treated with Dangui Xiaozhong ointment, 2 times /d. To observe the degree of foot swelling caused by carrageenin and its influence on pain threshold after 7 days. Results There was difference reduce in foot swelling of B, C groups than A group at 1, 2, 4, 5, 6 hour (P<0.01, P<0.05). B, C group after the injection of foot swelling had no obvious change. The analgesic effect of the drug was detected by detecting the change of the pain threshold in rats.B,C groups were higher than A group in pain threshold (P<0.01, P<0.05). C groups were higher than B group in pain threshold (P<0.01, P<0.05). Conclusion Dangui Xiaozhong ointment treatment of acute soft tissue injury in rats can effectively inhibit foot swelling and obvious analgesic effect, swelling and pain relief

关键词

丹归消肿膏/中药外敷/急性软组织损伤

Key words

Dangui Xiaozhong ointment/external application of Chinese medicine/acute soft tissue injury

分类

医药卫生

引用本文复制引用

杨大伟,宋雪,罗宗键,冷向阳..丹归消肿膏外敷对大鼠急性软组织损伤的消肿止痛作用[J].长春中医药大学学报,2017,33(4):536-538,3.

基金项目

吉林省科技厅项目(20080919). (20080919)

长春中医药大学学报

OACSTPCD

2095-6258

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