国际医药卫生导报2017，Vol.23Issue(15)：2355-2358,2365,5.DOI:10.3760/cma.j.issn.1007-1245.2017.15.011
腹腔镜下门奇静脉断流术加脾切除治疗门脉高压症的临床研究
Clinical study of laparoscopic portal azygous disconnection and splenectomy for portal hypertension
摘要
Abstract
Objective To evaluate the clinical effect of laparoscopic portal azygous disconnection and splenectomy for portal hypertension (PHT).Methods A total of 146 patients with portal hypertension were randomly divided into a control group and an observation group according to randomized controlled trial (RCT),73 for each group.The observation group were treated with laparoscopic portal azygous disconnection and splenectomy and the control group with portal azygous disconnection and splenectomy.The clinical effects of the two groups were compared.Results The operation time was longer,the intra-operative bleeding volume was lower,and the postoperative off-bed time,average exhaustion time,and hospitalization time were shorter in the observation group than in the control group (t=5.102 3,-31.508 6,-36.903 7,-12.099 9,-11.489 0,all P ＜ 0.05).There was no statistical difference in the hospitalization cost between the two groups (t=-0.592 5,P ＜ 0.05).The incidence of postoperative complications was 5.48％ in the observation group and was 30.14％ in the control group(x2=15.1615,P ＜ 0.05).The cognitive function,psychological function,somatic function,social function,and overall function were significantly better in the observation group than in the control group (t=6.5243,6.3899,6.8028,6.6980,47.0087,all P＜0.05).Conclusion Laparoscopic portal azygous disconnection and splenectomy for PHT have the advantages of less trauma,quick recovery,remarkable curative effect,and low incidence of postoperative complications,is feasible,safe,and effective,and can improve the patients' quality of life.关键词
肝硬化/门脉高压症/腹腔镜/门奇静脉断流术加脾切除Key words
Cirrhosis/Portal hypertension/Laparoscopy/Portal azygous disconnection and splenectomy引用本文复制引用
李国锋,谢永灿,谭彬斯,罗海军,邢专,刘传筹..腹腔镜下门奇静脉断流术加脾切除治疗门脉高压症的临床研究[J].国际医药卫生导报,2017,23(15):2355-2358,2365,5.基金项目
云浮市科技局科技攻关项目(2015B46) （2015B46）
