国际医药卫生导报2017，Vol.23Issue(15)：2435-2436,2.DOI:10.3760/cma.j.issn.1007-1245.2017.15.037
熊去氧胆酸治疗婴儿胆汁淤积症疗效观察
Ursodeoxycholic acid in treatment of infantile cholestasis
摘要
Abstract
Objective To observe the clinical efficacy ofursodeoxycholic acid (UDCA) in the treatment of infantile cholestasis.Methods 72 1-6 months infants with cholestasis were randomly divided into an observation group and a control group,36 cases for each group.Both groups were routinely and liver-protectively treated;in addition,the observation group orally took UDCA.The symptoms,signs,and liver biochemical indicators were compared between these two groups before and after the treatment.The extended medication times were observed.Results One week after medication,the total effective rate was 58.33％ in the observation group and 38.89％ in the control group,with a statistical difference (P ＜0.05).Two weeks after medication,the total effective rate was 86.11％ in the observation group and 52.78％ in the control group,with a statistical difference (P ＜0.01).No significant adverse reactions occurred in both groups during the observation period.Conclusions Orally taking UDCA in the treatment of infantile cholestasis is effective and has few side effects,so it is worth being clinically generalized.关键词
熊去氧胆酸/婴儿胆汁淤积症/疗效Key words
Ursodeoxycholic acid/Infantile cholestasis/Efficacy引用本文复制引用
钟琼..熊去氧胆酸治疗婴儿胆汁淤积症疗效观察[J].国际医药卫生导报,2017,23(15):2435-2436,2.
