中国实用神经疾病杂志2017，Vol.20Issue(14)：15-18,4.DOI:10.3969/j.issn.1673-5110.2017.14.005
缺血性脑卒中患者远期抑郁症状的发生率及相关因素分析
Analysis of the morbidity and related factors of long-term depressive symptoms in patients with ischemic stroke
摘要
Abstract
Objective To estimate the prevalence rate and related risk factors of long-term depressive symptoms (DS) in first-episode ischemic stroke (IS) patients with unilateral limb disorder.Methods After our prospective research having consecutively collected 126 patients who suffered from first-episode IS and unilateral limb disorder from November 2012 to July 2013,we gathered all patients'' general information and used NIHSS and modified Rankin Scale (MRS) to assess patients'' disease states.2~3 years after stroke,a follow-up research continued to use NIHSS,MRS,Barthel Index (BI),stroke specific quality of life (SS-QOL) and the Hamilton Depression Rating Scale (HDRS) to evaluate body and function impairment.The related factors for affecting long-term DS were identified by univariate analysis and were further researched by unconditioned Logistic regression analysis.Results Of the selected 126 patients,the occurrence rate of long-term DS was 38.60%(44/114).Mild,moderate and severe DS patients accounted for 19.30%(22/114),11.40%(13/114) and 7.90%(9/114),respectively.Multivariate unconditioned Logistic regression showed that education level (OR=2.847,95% CI:1.241 to 6.532),BI scores (OR=0.763,95% CI:0.648 to 0.916) and SS-QOL scores (OR=0.970,95% CI:0.937 to 0.989) were the influencing factors of long-term DS.As for population mean,the long-term BI scores of mild,moderate and severe DS patients (F=29.426,P<0.01) differed from SS-QOL scores (F=21.379,P<0.01).Conclusion The risk factor of long-term DS in first-episode ischemic stroke patients is high education level and the protective factors are high long-term BI scores and high quality of life.The less scores the long-term BI and SS-QOL present,the severer depressive symptoms patients suffer.Our study suggests that the important measures of improving long-term DS in IS patients may recover daily living ability and improve the quality of life.关键词
脑卒中/抑郁/影响因素/Logistic回归分析Key words
Stroke/Depression/Influencing factors/Logistic regression analysis分类
医药卫生引用本文复制引用
张莹,方岩,段金凤,徐辉,李春燕,姬卫东..缺血性脑卒中患者远期抑郁症状的发生率及相关因素分析[J].中国实用神经疾病杂志,2017,20(14):15-18,4.基金项目
河南省医学科技攻关计划项目(2011030040) （2011030040）
