临床误诊误治2017，Vol.30Issue(8)：53-56,4.DOI:10.3969/j.issn.1002-3429.2017.08.018
小儿围手术期医院获得性白色念珠菌血症五例临床分析
Clinical Analysis of 5 infants with Hospital-acquired Candida Albicans Bloodstream Infections during Perioperative Period
摘要
Abstract
Objective To investigate risk factors, clinical characteristics, diagnosis, treatment and preventative measures of infants with candida albicans bloodstream infections during perioperative period.Methods Clinical data of 5 infants with hospital-acquired candida albicans bloodstream infections during perioperative period admitted from October 8 to October 21, 2014was retrospectively analyzed, and related literature was reviewed.Results The pediatric critical illness score was (77.00±7.70) score on admission to the intensive care unit, and 4 infants had severe malnutrition.Preoperative diagnosis were 3 infants with short bowel syndrome, 1 infant with congenital megacolon allied disease and congenital esophageal atresia.All the 5 infants had fever, in whom 4 infants had sepsis induced by hospital-acquired candida albicans bloodstream infections, 2 infants had impaired liver function and 3 infants had thrombocytopenia.Central venous catheterization, gastric tube, urethral catheter, broad-spectrum antibiotic and total parenteral nutrition were given for the 5 infants, and there were 4 infants with gastrointestinal surgery and 3 infants with mechanical ventilation.All the 5 infants fitted to the diagnostic criteria of candida albicans bloodstream infections, and were treated with antifungal treatments after confirming diagnosis.In the 5 infants, lengths of ICU and hospital stays were (45.80±13.31)d and (97.40±20.63)d respectively.A total of 1 infant died in ICU stay, and 2 infants died within 90d of follow-up.Conclusion Fever is the mainly clinical manifestation of infants with candida albicans bloodstream infections during perioperative period.Clinicians should pay more attention to incidence of candidiasis for critical infants with congenital aplasia, prolonged hospitalization, severe malnutrition, lower PCIS scores and longer time of ductus detaining during perioperative period, and give adequately initial therapy to improve the prognosis.关键词
念珠菌血症/婴儿/围手术期Key words
Candidemia/Infant/Perioperative period分类
医药卫生引用本文复制引用
魏红霞,曹露露,张明军,谢伟,朱晓东..小儿围手术期医院获得性白色念珠菌血症五例临床分析[J].临床误诊误治,2017,30(8):53-56,4.基金项目
上海市科委科研计划项目(16411953000) （16411953000）
