中国内镜杂志2017,Vol.23Issue(8):18-22,5.DOI:10.3969/j.issn.1007-1989.2017.08.004
术中冲洗液在结直肠癌术后切口感染预防中的应用
Application of washing fluid in preventing postoperative incisional infection of colorectal cancer
摘要
Abstract
Objective To explore the application of washing fluid in the prevention of postoperative incision infection of colorectal cancer. Methods 350 patients with colorectal cancer underwent colorectal surgery from Jan. 2012 to Dec. 2015 were randomly divided into three groups: sterile saline, 0.50% metronidazole, 0.50% Povidone-iodine solution group, while part of the rinse liquid heated to 37 ~38℃ before use, then record the operation time, surgical site, postoperative incision infection, incision infection, timely delivery statistical analysis was performed by using single factor analysis and logistic multivariate regression analysis. Age, operation time, surgical site, type of irrigating fluid and temperature of flushing fluid were analyzed statistically. Results The incision infection rate of the patients ≥60 years old and the operation time ≥2 h was higher than the age <60 years, and the operation time was less than 2 h, P < 0.05, the difference was statistically significant; 0.50% metronidazole, 0.50% Povidone-iodine solution group, the infection rates of 0.50% metronidazole and 0.50% povidone-iodine group were 7.69% and 8.55%, respectively, which were significantly lower than those of the saline group 16.38% The infection rate of the rinsing fluid after heating was 7.22% and 14.71%, respectively, lower than that of the normal temperature rinsing solution (P < 0.05), the difference was statistically significant. Conclusions The risk factors of incisional infection in colorectal cancer patients with colorectal cancer were : ≥60 years of age and ≥2 h of operation, while 0.50%metronidazole, 0.50% povidone-iodine solution and heated washing fluid were protective factors. It can be applied to prevent incision infection after laparoscopic surgery.关键词
腹腔镜/结直肠癌/年龄/冲洗液Key words
laparoscopy/colorectal cancer/age/washing fluid分类
医药卫生引用本文复制引用
彭联明,蔡晶晶,何亚光,黄天磊..术中冲洗液在结直肠癌术后切口感染预防中的应用[J].中国内镜杂志,2017,23(8):18-22,5.基金项目
宁波市医学科技计划项目(No :2016A34) (No :2016A34)