中国全科医学2017，Vol.20Issue(z1)：1-4,4.
年轻隐匿型原发性卵巢功能不全患者的试管受精妊娠结局研究
IVF Pregnancy Outcome of Young Occult POI Patients Better than Aged Patients
摘要
Abstract
Objective To compare the IVF pregnancy outcomes of the pathological DOR patients (young occult POI patients) and the physiologic DOR patients (aged patients).Methods The clinical,laboratory and follow-up(including pregnancy outcomes)data of 275 cycles in 257 patients in accordance with the inclusion criteria (including 77 cycles of occult POI patients and 198 cycles of aged patients) undergoing IVF-ET in Reproductive Medicine Center of Guangdong Women and Children Hospital between January 2015 to December 2016 were retrospectively reviewed.Results Compere to the aged patients,the age,AFCs,AMH,infertility time,number of retrieved oocytes,number of mature oocytes and number of high quality embryos were lower in young occult POI patient.However,the embryo implantation rate,the biochemical pregnancy rate and the clinical pregnancy rate are preferable,the spontaneous abortion rate is lower in young occult POI patient,differences were statistically significant(P<0.05).Conclusion Although the ovarian reserve function and the number of oocytes of young occult POI patients has been already significantly reduced,the quality of oocytes has not been reduced,the young occult POI patients can still obtain good pregnancy outcomes.关键词
卵巢储备功能下降/高龄/原发性卵巢功能不全/试管受精/妊娠结局Key words
Diminished ovarian reserve/Advanced reproductive age/Primary ovarian insufficiency/In-vitro fertilization/Pregnancy outcomes分类
医药卫生引用本文复制引用
齐诠..年轻隐匿型原发性卵巢功能不全患者的试管受精妊娠结局研究[J].中国全科医学,2017,20(z1):1-4,4.基金项目
广东省自然科学基金(2016A030310318)——端粒与卵巢储备下降及其IVF/ICSI妊娠结局相关性的初步研究 （2016A030310318）
