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首页|期刊导航|中国全科医学|羟基磷灰石梯度涂层复合重组人骨形态发生蛋白-2股骨柄与SL-PLUS MIA股骨柄对全髋关节置换术后患者骨密度的影响

羟基磷灰石梯度涂层复合重组人骨形态发生蛋白-2股骨柄与SL-PLUS MIA股骨柄对全髋关节置换术后患者骨密度的影响

徐斌 周建华 杨军 牛鸣纲 李皓桓

中国全科医学2017,Vol.20Issue(z1):78-80,3.
中国全科医学2017,Vol.20Issue(z1):78-80,3.

羟基磷灰石梯度涂层复合重组人骨形态发生蛋白-2股骨柄与SL-PLUS MIA股骨柄对全髋关节置换术后患者骨密度的影响

Effects of HA Gradient Composite BMP Femoral Shank and SL-PLUS MIA Femoral Shank on Postoperative Bone Mineral Density in Patients with Total Hip Arthroplasty

徐斌 1周建华 1杨军 1牛鸣纲 1李皓桓2

作者信息

  • 1. 464300 河南省信阳市息县人民医院
  • 2. 武汉大学人民医院
  • 折叠

摘要

Abstract

Objective To research and analyze the effects of hydroxyapatite (HA) gradient composite recombinant human bone morphogenetic protein-2 (BMP) femoral shank and SL-PLUS MIA femoral shank on postoperative bone mineral density (BMD) in patients with total hip arthroplasty (THA).Methods A total of 60 patients (60 hips) with THA in Xixian County people′s Hospital were selected from February 2015 to February 2016 and all patients were divided into observation group (n=30) and control group (n=30) randomly.The SL-PLUS MIA femoral shank was used in the control group,while the observation group was treated with HA gradient coated BMP femoral shank,and the changes of hip joint activity,BMD,complication rate and Harris score were been observed.Results The hip joint activity and Harris score of two groups 12 months after the operation were higher than that before operation (P<0.05);each time point BMD of patients in the observation group,the difference was not statistically significant (P>0.05);In the control group,1,2,6,and 7 BMD after 6,12 months of operation were lower than 1 months (P<0.05),and the incidence of prosthesis loosening in the observation group was lower than that in the control group (P<0.05).Conclusion HA gradient coated BMP femoral shank and SL-PLUS MIA femoral shank THA both have good curative effect,which is helpful to improve hip function and improve hip mobility.However,patients treated with HA gradient coated BMP femoral stem with less bone loss,less risk of prosthesis loosening,and higher safety.

关键词

关节成形术,置换,髋/骨形态发生蛋白质2/羟基磷灰石类

Key words

Arthroplasty,replacement,hip/Bone morphogenetic protein 2/Hydroxyapatites

分类

医药卫生

引用本文复制引用

徐斌,周建华,杨军,牛鸣纲,李皓桓..羟基磷灰石梯度涂层复合重组人骨形态发生蛋白-2股骨柄与SL-PLUS MIA股骨柄对全髋关节置换术后患者骨密度的影响[J].中国全科医学,2017,20(z1):78-80,3.

中国全科医学

OA北大核心CSTPCD

1007-9572

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