中国全科医学2017,Vol.20Issue(z2):61-64,4.
中青年非妊娠女性碘营养状态与甲状腺疾病及功能的关系研究
Association of Iodine Nutrition and Thyroid Health Conditions among Middle-young Age Non Pregnant Women in Shengli Oilfield Areas
井源 1张山山 1高健 1姚霞 1陈启才1
作者信息
- 1. 257000 山东省东营市,胜利油田中心医院
- 折叠
摘要
Abstract
Objective To investigate relationship between iodine nutrition and thyroid disease among middle-young non-pregnant women in Shengli Oilfield areas.Methods A total of 931 subjects were investigated.Serum thyroid hormones,thyroid autoantibodies,and urinary iodine concentration were determined,and type B ultrasonography of thyroid gland was performed in all participants.Results The median level of urinary iodine in 931 women was 113.4 μg/L.Thyroid disease group was 413 (44.36%) and the median level of urinary iodine was 112.7 μg/L.There was no significant statisical difference in median level of urinary iodine between thyroid disease group and normal group(P>0.05).There was no significant difference in urinary iodine levels between the groups of thyroid diseases (P>0.05).The levels of T3,T4,FT3,FT4 and TSH in the patients with different urinary iodine levels were not statistically significant(P>0.05).TPOAb positive group and TgAb positive group urinary iodine levels were significantly higher than TPOAb negative group and TgAb negative group(P<0.05).Multivariate Logistic regression analysis showed that age〔OR=1.040,95%CI(1.009,1.071)〕 and thyroid antibody positive〔OR=5.680,95%CI(3.864,8.349)〕 were important risk factors for middle-young non-pregnant women thyroid disease,and urinary iodine levels〔OR=0.985,95%CI(0.822,1.182)〕 was no correlation.Conclusion Iodine uptake in is sufficient in Shengli Oilfield areas.The thyroid disease may be associated with age and thyroid antibodies,not to the iodine status.关键词
甲状腺疾病/碘/甲状腺功能亢进症/甲状腺功能减退症Key words
Thyroid diseases/Iodine/Hyperthyroidism/Hypothyroidism分类
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井源,张山山,高健,姚霞,陈启才..中青年非妊娠女性碘营养状态与甲状腺疾病及功能的关系研究[J].中国全科医学,2017,20(z2):61-64,4.