中国全科医学2017,Vol.20Issue(z2):107-109,3.
糖代谢异常与甲状腺容积变化的相关性研究
Relationship between Abnormal Glucose Metabolism and the Transformation of Thyroid Volume
摘要
Abstract
Objective To explore the association between glucose metabolism and thyroid volume in a iodine sufficient area.Methods A total of 1 224 inhabitants above ten years in community of Guiyang urban areas were investigated from October 2009 to February 2010 by adopting stratified cluster sampling method.All subjects were asked to fulfill the questionnaires and to measure the height,weight;and to undertake oral glucose tolerance test(diabetic patients with 80 g of instant noodles).Venous blood samples were drawn to measure 25(OH)D,parathyroid hormone(PTH),thyroid stimulating hormone(TSH),serum uric acid(UA),fasting plasma glucose,2 h postprandial plasma glucose and fasting insulin.Urine sample was measured urine iodine.Ultrasound was measured the length of thyroids.The inhabitants was divided into controls,pre-diabetes,and diabetes according glucose level.Results Mean thyroid volume was higher in the diabetes(6.93±3.19)ml group than in the controls(6.29±2.15)ml(P=0.007).There was a relation between thyroid volume and thyroid stimulating hormone,insulin,insulin resistance(r=0.115,P<0.01;r=0.138,P<0.01;r=0.148,P<0.01).The pre-diabetes and diabetes were risk factors for thyroid volume(P<0.05).Conclusion Abnormal glucose metabolism may be an independent risk factor for thyroid volume.关键词
胰岛素/胰岛素抵抗/糖代谢紊乱/甲状腺容积Key words
Insulin/Insulin resistance/Abnormal glucose metabolism/Thyroid volume分类
医药卫生引用本文复制引用
曹婷,张巧,时立新,彭年春,徐淑静,张松,张淼,胡颖..糖代谢异常与甲状腺容积变化的相关性研究[J].中国全科医学,2017,20(z2):107-109,3.基金项目
贵州省科学技术厅资助项目[黔科合LG字(2011)016号] (2011)