中国药房2017，Vol.28Issue(23)：3188-3191,4.DOI:10.6039/j.issn.1001-0408.2017.23.05
桃仁-大黄药对在中药方剂中发挥功效的相关因素分析
Analysis of Factors Related to Efficacy of Peach kernel-Rheum palmatum Couplet Medicines in TCM For-mula
摘要
Abstract
OBJECTIVE:To study the influential factors related to efficacy of Peach kernel-Rheum palmatum couplet medi-cines in TCM formula,and to reveal the general regularity of compatibility environment,common ratio,processing variety and dosage forms of P. kernel-R. palmatum couplet medicines. METHODS:Using Chinese Medical Prescription Selected Dictionary ed-ited by Peng Huairen as data source,142 formulas of P. kernel-R. palmatum couplet medicines were collected. By establishing data-base,compatibility types of P. kernel-R. palmatum couplet medicines,as well as common ratio,processed prodact,dosage form were classified statistically. The influential factors related to efficacy of P. kernel-R. palmatum couplet medicines with different pro-portions were summarized. RESULTS:The efficacy of P. kernel-R. palmatum couplet medicines could be divided into 6 aspects and 11 roles,including activating blood circulation to dissipate blood stasis(activating blood to relieve pain,promoting blood circula-tion to eliminate disease,activating blood to promote menstruation,breaking stagnant and eliminating blood stasis),eliminating carbuncle and detoxicating(cleaning intestine and clearing away the pathogenic heat of lung,eliminating carbuncle and expelling pus,eliminating sore and detoxicating),expelling the pathogenic heat to loosen the bowels,warming yang for dispelling cold,forti-fying the spleen and nourishing the stomach,relaxing tendon and activating blood. The compatibility environment of P. kernel-R. pal-matum couplet medicines were mainly compatible with TCM for activating qi to eliminate stasis,activating blood to promote menstru-ation,breaking stagnant and eliminating blood stasis,expelling the pathogenic heat to expel stasis. The ratio of P. kernel to R. palma-tum ranged 1 : 8-4 : 1,and the ratio ranged 1 : 8-3 : 1 when performing the role of actirating blood circalation to dissipate blood stasis. Common processed products were crude P. kernel and prepared R. palmatum. Common dosage forms were mainly decoction,pill and powder. CONCLUSIONS:Compatibility environment,ratio,processing varieties,dosage forms influence the effects of P. kernel-R. palmatum couplet medicines,especially compatibility environment.关键词
桃仁-大黄/药对/配伍环境/配比/炮制品种/剂型/功效Key words
Peach kernel-Rheum palmatum/Couplet medicines/Compatibility environment/Ratio/Processing varieties/Dos-age forms/Efficacy分类
医药卫生引用本文复制引用
郭玲玲,颜永刚,王红艳,尹立敏,邓翀..桃仁-大黄药对在中药方剂中发挥功效的相关因素分析[J].中国药房,2017,28(23):3188-3191,4.基金项目
国家自然科学基金资助项目(No.30901970) （No.30901970）
陕西省教育厅专项科研计划项目(No.14JK1204) （No.14JK1204）
陕西省教育厅重点实验室科研计划项目(No.13JS030) （No.13JS030）
