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丹参水溶性有效成分对内皮祖细胞功能的影响

杨锦秀 毛威

中国药理学通报2017,Vol.33Issue(9):1203-1206,4.
中国药理学通报2017,Vol.33Issue(9):1203-1206,4.DOI:10.3969/j.issn.1001-1978.2017.09.005

丹参水溶性有效成分对内皮祖细胞功能的影响

Effects of hydrosoluble active constituent ofSalvia miltiorrhiza Bge on endothelial progenitor cell functions

杨锦秀 1毛威1

作者信息

  • 1. 浙江中医药大学附属第一医院心内科,浙江 杭州 310006
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摘要

Abstract

The hydrosoluble active constituent of Salvia miltiorrhiza Bge has a wide range of physiological activities and pharmacological effects.Endothelial progenitor cells(EPCs) comprise a cell population that has the capacity to circulate, proliferate and differentiate into mature endothelial cells but that has not yet acquired characteristic mature endothelial markers nor formed precursor cells of blood vessels.It was found that the hydrosoluble active constituent of Salvia miltiorrhiza Bge could protect endothelial functions through modulation of EPCs functions, thus exerting therapeutic effects in endothelium injured related diseases.This paper reviewed the effects of the hydrosoluble active constituent of Salvia miltiorrhiza Bge on EPCs functions.We hope that the paper could provide a reference for further utilization of hydrosoluble active constituent of Salvia miltiorrhiza Bge.

关键词

丹参/水溶性/成分/内皮祖细胞/功能/影响

Key words

Salvia miltiorrhiza Bge/hydrosolubility/constituent/endothelial progenitor cells/function/effect

分类

医药卫生

引用本文复制引用

杨锦秀,毛威..丹参水溶性有效成分对内皮祖细胞功能的影响[J].中国药理学通报,2017,33(9):1203-1206,4.

基金项目

国家自然科学基金资助项目(No 81400192) (No 81400192)

中国药理学通报

OA北大核心CSCDCSTPCD

1001-1978

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