重庆医学2017，Vol.46Issue(23)：3198-3200,3.DOI:10.3969/j.issn.1671-8348.2017.23.009
糖尿病足溃疡患者截肢相关因素分析
Analysis of related factors of diabetes foot ulcer amputation
摘要
Abstract
Objective To explore related factors of amputation in patients with diabetes foot ulcer(DFU) and provide the evidence of reducing amputation rate.Methods A total of 307 inpatients with DFU in this hospital from October 2013 to December 2015 were collected and divided into amputation group(n=28) and non-amputation group(n=279).The clinical data and laboratory data were treated with single variable analysis and multivariate Logistic regression analysis.Results Single variable analysis showed that hospitalization time,hyper-sensitive C-reactive(hs-CRP) and fibrinogen(FIB) level were significantly increased in amputation group(P＜0.05) when compared with non-amputation group,and the hemoglobin (Hb) level,high-density lipoprotein cholesterol(HDL) and serum albumin (ALB) level in amputation group were markedly lower than in non-amputation group(P＜0.05).Amputation rate was significantly different among different Wagner grades (P=0.000).Multivariate Logistic regression analysis showed that hospitalization time,Wagner grade were independent risk factors of amputation in patients with DFU,OR values were 1.024(95％CI:1.009-1.039) and 2.779 (95％CI:1.753-4.404),respectively.While HDL was a protective factor of amputation in patient with DFU (OR=0.161;95％CI:0.036-0.729).Conclusion The higher the rank of Wanger in DFU patients are,the longer hospital stay and the higher amputation risk become.HDL is the protective factor of DFU amputation.关键词
糖尿病足/溃疡/截肢术/危险因素Key words
diabetic foot/ulcer/amputation/risk factors分类
医药卫生引用本文复制引用
傅仕敏,程庆丰,邓书华,宋颖,梅玫,刘智平..糖尿病足溃疡患者截肢相关因素分析[J].重庆医学,2017,46(23):3198-3200,3.基金项目
国家临床重点专科建设项目[财社(2011)170号 （2011）
重庆医科大学附属第一医院护理科研基金(HLJ2015-27)]. （HLJ2015-27）
