重庆医学2017,Vol.46Issue(23):3222-3225,4.DOI:10.3969/j.issn.1671-8348.2017.23.017
咪达唑仑在结肠镜检查清醒镇静中对心肺功能的影响
Effect of midazolam on cardiopulmonary function during colonoscopy
管恩翠 1孙金刚 2王志胜 3田峰1
作者信息
- 1. 山东省临沂市沂水中心医院消化内科 276400
- 2. 山东省临沂市沂水中心医院心内科 276400
- 3. 北京市心肺血管疾病研究所/首都医科大学附属北京安贞医院心内科,100029
- 折叠
摘要
Abstract
Objective To investigate the effect of midazolam on cardiopulmonary function during colonoscopy.Methods From June 2014 to June 2015,214 patients underwent colonoscopy were randomly divided into two groups:109 patients in the midazolam group and 105 patients in the non-sedated group(control group).systolic blood pressure(SBP),diastolic blood pressure (DBP),heart rate (HR) and peripheral blood oxygen partial pressure (SpO2) in the two groups before and after colonoscopy were compared.Results In the midazolam group,SBP and DBP decreased more during colonoscopy than in the control group.However,the frequency with a significant change in SBP was similar in both groups.During colonoscopy,HR andSpO2 decreased more in the midazolam group compared to those in the control group.SpO2 levels returned to normal after the procedure in two groups.Conclusion Midazolam has a tolerable effect on cardiopulmonary function and may be safely used during colonoscopy.关键词
结肠镜检查/咪达唑仑/清醒镇静/心肺功能Key words
colonoscopy/midazolam/conscious sedation/cardiopulmonary function分类
医药卫生引用本文复制引用
管恩翠,孙金刚,王志胜,田峰..咪达唑仑在结肠镜检查清醒镇静中对心肺功能的影响[J].重庆医学,2017,46(23):3222-3225,4.