儿科药学杂志2017，Vol.23Issue(8)：46-49,4.DOI:10.13407/j.cnki.jpp.1672-108X.2017.08.017
荔大前合剂质量标准研究
Quality Standard of Lidaqian Mixture
景霞 1许静 1许泽君 1刘瑶1
作者信息
- 1. 南京医科大学附属儿童医院,江苏南京210008
- 折叠
摘要
Abstract
Objective:To establish the quality standard of Lidaqian mixture.Methods:Plantago depressa Willd.was identified by thin layer chromatography (TLC).HPLC was adopted to determine the content of buddleoglucoside in Lidaqian mixture.The Agilent-C18 column (150 mm ×4.6 mm,5 pm) was used with the mobile phase of methanol-0.5％ acetic acid (55∶45),the detection wavelength was at 326 nm.Results:TLC identification method was simple and feasible with specificity.The calibration curve was linear over the ranges of 1.217 to 7.303 μg/mL (r =0.999,6) for buddleoglucoside when the sample volumn was 20 μL.The average recovery was 99.54％,RSD was 1.5％ (n =9).Conclusion:The method was simple,accurate and specific for quality control of Lidaqian mixture.关键词
荔大前合剂/质量标准/车前草/薄层色谱/蒙花苷/高效液相色谱法Key words
Lidaqian mixture/quality standard/Plantago depressa Willd./TLC/buddleoglucoside/HPLC method分类
医药卫生引用本文复制引用
景霞,许静,许泽君,刘瑶..荔大前合剂质量标准研究[J].儿科药学杂志,2017,23(8):46-49,4.
