心理科学进展2017,Vol.25Issue(8):1310-1320,11.DOI:10.3724/SP.J.1042.2017.01310
基因与环境的交互作用:来自差别易感性模型的证据
The interaction between gene and environment:Evidence from differential susceptibility model
摘要
Abstract
According to the differential susceptibility model,individuals with certain genetypes are not only more vulnerable than others to the negative effects of adversity,but also disproportionately susceptible to the beneficial effects of supportive and enriching rearing environment.With the advancement of quantitative genetics and molecular genetics,a great many researches on the effect of gene-environment interaction on children's development have emerged in recent years.For example,researches have been done regarding the interaction between environment (such as maternal sensitivity,stressful life events and family upbringing)and five candidate genes-5-HTTLPR,DRD4,MAOA,COMT and BDNF-all of which support the differential susceptibility model.The underlying mechanisms of gene-environment interaction,racial and gender differences between individuals carrying vulnerable genes as well as further estimation of vantage sensitivity hypothesis are all important directions of future researches in this area.关键词
基因-环境交互作用/基因/差别易感性/优势敏感性Key words
gene-environment interaction/gene/differential susceptibility/vantage sensitivity分类
社会科学引用本文复制引用
赵德懋,冯姝慧,邢淑芬..基因与环境的交互作用:来自差别易感性模型的证据[J].心理科学进展,2017,25(8):1310-1320,11.