西南国防医药2017，Vol.27Issue(8)：802-805,4.DOI:10.3969/j.issn.1004-0188.2017.08.008
起搏器围手术期不同抗凝方案安全性评价
Safety of different anticoagulant methods in perioperative period of pacemaker implantation
安宁 1曹瑞1
作者信息
- 1. 719000陕西榆林,榆林市第四(星元)医院心血管内科
- 折叠
摘要
Abstract
Obeetive To compare the safety of different anticoagulant methods in the perioperative period of pacemaker implantation.Methods The clinical data of a total of 86 patients who had been admitted to our hospital and had taken anticoagulants for a long time to install a permanent pacemaker were analyzed retrospectively.The patients were divided into groups A,B and C according to different anticoagulant methods.Warfarin therapy was adopted in Group A (n=28) in the perioperative period without interruption;warfarin therapy in group B(n=29) was stopped 3-5 days before pacemaker implantation,after which no anticoagulation was conducted,and resumed 12 hours after the operation;warfarin therapy in group C (n=29) was stopped 3-5 days before pacemaker implantation,after which bridging therapy with low molecular weight heparin (LMWH) was conducted,and resumed 12 hours after the operation.The length of stay (LOS),and incidence of complications associated with sac and thromboembolic events among the three groups were compared.Results The LOS was the shortest in group A and the longest in group C,showing significant difference among the three groups (P ＜ 0.05).The total incidence of complications associated with sac was 3.57％ in group A,6.90％ in group B and 17.24％ in group C.The incidence in group A was the lowest and that in group C was the highest,but the difference in the complications associated with sac and thromboembolic events among the three groups showed no significant difference (P ＞ 0.05).Conchusion The uninterrupted use of warfarin in perioperative period of pacemaker implantation is an ideal anticoagulation method.The total incidence of complications associated with sac in relatively low.关键词
心脏起搏器/华法林/围手术期/并发症Key words
cardiac pacemaker/warfarin/perioperative period/complication分类
医药卫生引用本文复制引用
安宁,曹瑞..起搏器围手术期不同抗凝方案安全性评价[J].西南国防医药,2017,27(8):802-805,4.
