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匹伐他汀对不稳定性心绞痛患者血清CRP和ET的影响

谢辉 曹薇 符江琳

西南国防医药2017,Vol.27Issue(8):805-807,3.
西南国防医药2017,Vol.27Issue(8):805-807,3.DOI:10.3969/j.issn.1004-0188.2017.08.009

匹伐他汀对不稳定性心绞痛患者血清CRP和ET的影响

Impacts of pitavastatin on serum CRP and ET in patients with unstable angina

谢辉 1曹薇 1符江琳1

作者信息

  • 1. 442000湖北十堰,湖北医药学院附属人民医院心内科
  • 折叠

摘要

Abstract

Objective To analyze the changes in serum C-reactive protein (CRP) and endothelin (ET) levels in the treatment of early unstable angina in senile patients with pitavastatin.Methods A total of 80 senile patients diagnosed as early unstable angina in our hospital were selected and randomly divided into an observation group and a control group (n=40,respectively).The control group was treated with conventional therapy with essential medicine and the observation group was additionally treated with pitavastatin by oral administration for one month.The changes in the serum CRP and ET levels before and after the treatment between the two groups were compared.Results The post-treatment serum CRP and ET content in the two groups decreased significantly (P < 0.05),and the decrease in the observation group was greater than that in the control group (P < 0.05);the incidence of adverse drug reactions between the two groups showed no statistical difference (P > 0.05).Conclusion Pitavastatin has obvious effects and high safety in the treatment of early unstable angina in senile patients,so it is worthy of clinical popularization.

关键词

匹伐他汀/不稳定性心绞痛/C-反应蛋白/内皮素

Key words

pitavastatin/unstable angina/CRP/ET

分类

医药卫生

引用本文复制引用

谢辉,曹薇,符江琳..匹伐他汀对不稳定性心绞痛患者血清CRP和ET的影响[J].西南国防医药,2017,27(8):805-807,3.

西南国防医药

OACSTPCD

1004-0188

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