西南国防医药2017，Vol.27Issue(8)：822-824,3.DOI:10.3969/j.issn.1004-0188.2017.08.015
TGAb、TMAb和TPOAb诊断在桥本甲状腺炎诊断中的价值
Value of TGAb, TMAb and TPOAb in diagnosis of hashimoto thyroiditis
贺帅 1张力2
作者信息
- 1. 710054西安,西安市第九医院检验科
- 2. 陕西省友谊医院检验科
- 折叠
摘要
Abstract
Objective To analyze the value of thyroglobulin antibodies (TGAb),thyroid microsomal antibody (TMAb) and antithyroid peroxidase antibody (TPOAb) in the diagnosis of hashimoto thyroiditis.Methods A total of 57 patients with suspected hashimoto thyroiditis were selected and 54 patients were diagnosed with hashimoto thyroiditis with clinical or pathological diagnosis as the gold standard.The TGAb,TMAb and TPOAb levels of all patients were detected to calculate the sensitivity,specificity and compliance of TGAb,TMAb and TPOAb levels in the diagnosis of hashimoto thyroiditis.Results The TGAb,TMAb and TPOAb levels of patients with hashimoto thyroiditis were significantly higher than the normal reference value (P ＜ 0.05);there were significant differences in the diagnosis sensitivity and coincidence rate among the three indexes (P ＜ 0.05),and the sensitivity and coincidence rate of TPOAb were the highest,but the specificity of TGAb was significantly higher than that of TPOAb and TMAb (P ＜ 0.05).Conclusion The detection of TPOAb and TGAb levels has high value in the diagnosis of hashimoto thyroiditis,but appropriate index should be selected according to specific circumstances to assist the diagnosis.For example,TPOAb with higher sensitivity is preferred for disease screening,while TGAb with higher specificity is preferred for clinical diagnosis.关键词
桥本甲状腺炎/诊断/甲状腺球蛋白抗体/甲状腺微粒体抗体/抗甲状腺过氧化物酶抗体Key words
hashimoto thyroiditis/diagnosis/TGAb/TMAb/TPOAb分类
医药卫生引用本文复制引用
贺帅,张力..TGAb、TMAb和TPOAb诊断在桥本甲状腺炎诊断中的价值[J].西南国防医药,2017,27(8):822-824,3.
