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生物纳米孔分析技术研究进展

尚积祯 李志 郗冬梅 张书圣

应用化学2017,Vol.34Issue(8):855-867,13.
应用化学2017,Vol.34Issue(8):855-867,13.DOI:10.11944/j.issn.1000-0518.2017.08.170103

生物纳米孔分析技术研究进展

Progress in Biological Nanopore-based Analysis Technology

尚积祯 1李志 2郗冬梅 2张书圣2

作者信息

  • 1. 曲阜师范大学化学与化工学院,山东省生命有机分析重点实验室 山东 曲阜273165
  • 2. 临沂大学化学化工学院,山东省肿瘤标志物检测技术重点实验室 山东 临沂276005
  • 折叠

摘要

Abstract

Biological nanopore sensing has been developed as an attractive single-molecule tool with advantages of being rapid, low-cost, and label-free.Nanopores are not only being widely developed for DNA sequencing, but they also have been utilized to analyze a wide range of analytes at the single-molecule level.This review summarizes and prospects the principle of the nanopore analysis and nanpore category, with an emphasis on the progress in nanopore-based DNA sequencing and single-molecule analysis.

关键词

生物纳米孔/DNA测序/单分子分析

Key words

biological nanopore/DNA sequencing/single-molecule analysis

分类

化学化工

引用本文复制引用

尚积祯,李志,郗冬梅,张书圣..生物纳米孔分析技术研究进展[J].应用化学,2017,34(8):855-867,13.

基金项目

国家自然科学基金(21405073,21535002)资助 (21405073,21535002)

Supported by the National Natural Science Foundation of China(No.21405073, No.21535002) (No.21405073, No.21535002)

应用化学

OA北大核心CSCDCSTPCD

1000-0518

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