中国实验动物学报2017，Vol.25Issue(4)：356-361,6.DOI:10.3969/j.issn.1005-4847.2017.04.003
基于3.0T磁共振成像系统初步观察WHBE兔脑部形态解剖结构
Preliminary observation of the anatomical structures of the brain in WHBE rabbits by 3.0 T magnetic resonance imaging system
摘要
Abstract
Objective To observe the morphological structures of WHBE rabbit brain in vivo based on 3.0 T magnetic resonance imaging system (MRI), accumulate the basic biological data of WHBE rabbit brain imaging, and provide a background information to further expand the WHBE rabbit application.Methods Nine healthy adult male WHBE rabbits were intravenously anesthetized with 3% pentobarbital sodium.3.0 T MRI plus rabbit brain dedicated coil was used to perform routine transverse and sagittal scans, and the size of brain structures were measured.Results MRI scanning can be successfully performed to obtain sagittal and transverse T2WI or T1WI images of WHBE rabbit brain in vivo, and can be clearly observed the basic structures of WHBE rabbit brains in vivo, such as olfactory bulb, cerebrum, cerebellum and pituitary gland.In addition, high signal was found in the hippocampus of the left and right temporal lobes in 4 rabbits with T2WI, but also low signal appeared in the corresponding regions in T1WI, and the others were not abnormal.Meanwhile, the reference data of frontal lobe, hippocampus, cerebrum, lateral ventricles, pituitary gland and other related anatomical structures were also obtained.Conclusions Using the 3.0 T magnetic resonance imaging system and rabbit brain coil,the morphological and anatomical structures of rabbit brain can be clearly observed, and the basic imaging data of WHBE rabbits brain have been established preliminarily.关键词
磁共振成像/WHBE兔/脑/解剖结构Key words
Magnetic resonance imaging/WHBE rabbits/Brain/Anatomical structures分类
生物科学引用本文复制引用
潘永明,金平,徐剑钦,刘军平,蔡兆伟,许茂盛,陈民利..基于3.0T磁共振成像系统初步观察WHBE兔脑部形态解剖结构[J].中国实验动物学报,2017,25(4):356-361,6.基金项目
浙江省科技厅公益性项目(2016C37092) （2016C37092）
浙江省医药卫生科研基金项目 (2017KY123) （2017KY123）
浙江中医药大学比较医学创新团队(XTD201301) （XTD201301）
浙江中医药大学校级科研基金项目(2017ZZ01). （2017ZZ01）
