浙江医学2017，Vol.39Issue(13)：1053-1056,1060,5.DOI:10.12056/j.issn.1006-2785.2017.39.13.2015-369
磁敏感加权成像评价急性脑梗死后静脉血氧饱和度及局部脑氧代谢改变
Assessment of venous blood oxygen saturation and regional cerebral oxygen metabolism by MR susceptibility weighted imaging in patients with acute cerebral infarction
摘要
Abstract
Objective To evaluate venous blood oxygen saturation and regional oxygen metabolism changesby MR susceptibility weighted imaging MR-SWI in patients with acute cerebral infarction.Methods Thirty six patients with acute cerebral infraction admitted from January 2012 to June 2014 and 25 heaithy subjects were enrolled in the study.All subjects received MRI examinations,including T1W,T2W,DWI and SWI;for infarcted patients the examination was performed within 14d after clinical onset.The phase values of superior sagittal sinuses,straight sinuses and infarction volume was measured,venous dilatation around lesions was observed,and NIHSS scores were measured or evaluated.Among 36 patients,the infacted location was in basal ganglia region and periventricular region (n=21),cerebral lobe region (n=7) and pons region (n=8),meanwhile,the admission time from onset was 1-7 d in 17 cases,and 8-14 d in 19 cases.Results The phase values of straight sinus in cerebral infarction group(2 574.91 ± 223.20) were significantly lower than those in control group(2 908.49 ± 207.56)(P＜0.001).The phase values of straight sinus in the basal ganglia region and the periventricular region,the cerebral lobe region and the pons region in infarcton group (2 523.00 ± 215.80,2 668.19 ± 229.66,2 629.55 ± 224.79) were lower than those in control group (all P＜ 0.05).The phase values of superior sagittal sinuses (2 205.09 ±65.73) in patients with cerebral lobe infarction significantly increased,compared patients with the basal ganglia region and periventricular region,the pons region infarction and the control group (2 126.55 ±62.16,2 137.24 ±51.31,2 112.94 ±48.81)(P＜0.05).Venous dilatation was observed in 21 infarcted patients,which occurred from d1 to d7 of onset in 13 cases and from d8 to d14 in 8 cases.Spearman relativity analysis revieled that venous dilation was significantly related to the infarction volume and time.The venous dilatation around the lesions was significantly correlated with the infarction volume and the time of onset(P＜0.05).Conclusion SWl can quantitatively measure the phase values of intracranial venous blood and can detect venous dilation around the lesions in patients with acute cerebral infarction,which may provide alternative references for clinical noninvasive assessment of hypoxia of regional brain tissue and oxygen metabolism of partial infarction tissue in patients with cerebral infarction.关键词
脑梗死/MRI/磁敏感加权成像/血氧代谢Key words
Cerebral infarction/MRI/Susceptibility weighted imaging/Blood oxygen metabolism引用本文复制引用
曹志坚,章正祥,刘玉凤,张丽萍,侯群,许茂盛..磁敏感加权成像评价急性脑梗死后静脉血氧饱和度及局部脑氧代谢改变[J].浙江医学,2017,39(13):1053-1056,1060,5.基金项目
浙江省中医药管理局(20122B035) （20122B035）
