浙江医学2017，Vol.39Issue(13)：1094-1096,3.DOI:10.12056/j.issn.1006-2785.2017.39.13.2015-901
血清AQP4水平与脑出血周围水肿体积相关性的研究
Association between serum AQP4 level and brain edema volume following intracerebral hemorrhage
章晓英 1宋水江 2迟淑梅 1王超3
作者信息
- 1. 310007 杭州市第七人民医院神经内科
- 2. 浙江大学医学院附属第二医院神经内科
- 3. 浙江大学医学院附属第二医院影像科
- 折叠
摘要
Abstract
Objective To investigate the association betweenserum AQP4 level and brain edema volume following intracerebral hemorrhage(ICH).Methods Serum AQP4 was measured in 50 patients with spontaneous intracerebral hemorrhage within 3-7 d after onset.Hematoma volume,peripheral edema volume and relative edema were measured at the same time by CT scan.Results Serum AQP4 levels and relative edema volume at 7d following ICH were significantly increased,compared to those at d3.Serum AQP4 levels were positively correlated withrelative edema volume at d3 and d7 (r=0.555,P＜0.01).Conclusion AQP4 may be involved in the development of cerebral edema and cerebral injury after ICH,indicating that AQP4 might be a new therapeutic targed for brain edema after cerebral hemorrhage.关键词
水通道蛋白4/脑出血/脑水肿Key words
Aquaporin4/Intracerebral hemorrhage/Brain edema引用本文复制引用
章晓英,宋水江,迟淑梅,王超..血清AQP4水平与脑出血周围水肿体积相关性的研究[J].浙江医学,2017,39(13):1094-1096,3.
