肿瘤防治研究2017，Vol.44Issue(8)：558-561,4.DOI:10.3971/j.issn.1000-8578.2017.17.0028
HOXB13在前列腺癌中的作用及机制研究进展
Research Progress on Functions of HOXB13 in Prostate Cancer and Related Mechanisms
摘要
Abstract
As a member of homeobox gene,HOXB13 is frequently expressed in prostate tissues and can regulate the growth and development of prostate tissues.The incidence of G84E mutation in Euramerican prostate cancer patients with HOXB 13 is higher than that of normal population,while a novel HOXB 13 gene mutation G135E is associated with increased prostate cancer risk in China.High expression of HOXB13 in prostate cancer tissues indicates poor prognosis of patients.This paper reviews the functions of HOXB 13 in prostate cancer and related mechanisms.关键词
HOXB13/前列腺癌/肿瘤发生/肿瘤转移Key words
HOXB13/Prostate cancer/Tumorigenesis/Metastasis分类
医药卫生引用本文复制引用
巩师毅..HOXB13在前列腺癌中的作用及机制研究进展[J].肿瘤防治研究,2017,44(8):558-561,4.
