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芎黄合剂治疗重症肺炎合并胃肠功能障碍临床观察

朱桂松 吴同启 傅元冬 陈畅泉 周媛媛

中国中西医结合杂志2017,Vol.37Issue(8):909-912,4.
中国中西医结合杂志2017,Vol.37Issue(8):909-912,4.DOI:10.7661/j.cjim.20170623.141

芎黄合剂治疗重症肺炎合并胃肠功能障碍临床观察

Xionghuang Mixture for Severe Pneumonia Complicated with Gastrointestinal Dysfunction

朱桂松 1吴同启 1傅元冬 1陈畅泉 1周媛媛1

作者信息

  • 1. 南京市中医院重症医学科 南京 210001
  • 折叠

摘要

Abstract

Objective To observe the clinical efficacy of Xionghuang Mixture (XHM) in treatment of severe pneumonia complicated with gastrointestinal dysfunction.Methods Sixty patients with severe pneumonia complicated with gastrointestinal dysfunction were randomly assigned to the control group and the XHM group,30 in each group.Patients in the control group were treated with standard Western medical method,while those in the XHM group additionally took XHM.The therapeutic course lasted for 14 days.The levels of inflammation factors (serum CRP,PCT,IL-6,and IL-8),clinical pulmonary infection score (CPIS),and gastrointestinal dysfunction score (GIDS) were compared between the two groups before treatment,and at day 7 and 14 after treatment.The 28-day mortality was also detected.Results The inflammation levels,CPIS and GIDS were all decreased significantly at day 7 and 14 after treatment in both groups (P<0.05,P<0.01).The indices mentioned above decreased at day 7 and 14 in the XHM group,as compared with the control group (P<0.05,P<0.01).The 28-day mortality was lower in the XHM group [6.7% (2/30)],as compared with the control group [16.7% (5/30),P>0.05].Conclusion XHM could decrease the inflammation level and promote the recovery of gastrointestinal function of patients with severe pneumonia complicated with gastrointestinal dysfunction.

关键词

芎黄合剂/重症肺炎/胃肠功能障碍

Key words

Xionghuang Mixture/severe pneumonia/gastrointestinal dysfunction

引用本文复制引用

朱桂松,吴同启,傅元冬,陈畅泉,周媛媛..芎黄合剂治疗重症肺炎合并胃肠功能障碍临床观察[J].中国中西医结合杂志,2017,37(8):909-912,4.

基金项目

南京市医学科技发展项目(No.YKK14144) (No.YKK14144)

中国中西医结合杂志

OA北大核心CSCDCSTPCDMEDLINE

1003-5370

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