动物营养学报2017，Vol.29Issue(3)：769-775,7.DOI:10.3969/j.issn.1006-267x.2017.03.006
苦味受体的生物学特征、信号转导机制及苦味剂和苦味抑制剂对苦味受体的影响
Bitter Taste Receptors: Biological Characteristics, Signal Transduction Mechanism, and Effects of Bitters and Bitter Taste Inhibitors
曹英东 1李方方 1张勇 1黄铁军2
作者信息
- 1. 沈阳农业大学畜牧兽医学院,沈阳110866
- 2. 乐达(广州)香味剂有限公司,广州510530
- 折叠
摘要
Abstract
Bitter taste receptor (TAS2Rs) is a kind of G-protein coupled receptor (GPCR),which is encoded by a gene family composed of 30 genes.Bitterness can keep animals away from the toxic and harmful substances.When the animal tasted bitter substances,they will stimulate the tongue taste buds taste receptor cells to express TAS2Rs,then lead to a series of downstream signal transduction pathway,and the information is ultimately spread to the brain through drum rope nerve and glossopharyngeal nerve.It makes animals generate feelings of disgust,refuse to intake these bitter substances.In this paper,biological characteristics,signal transduction mechanism of bitter taste receptors,and the effects of bitters and bitter taste inhibitors on bitter taste receptors were briefly reviewed.关键词
苦味受体/生物学特征/信号转导机制/苦味剂/苦味抑制剂Key words
bitter taste receptor/biological characteristic/signal transduction mechanism/bitter/bitter taste inhibitor分类
农业科技引用本文复制引用
曹英东,李方方,张勇,黄铁军..苦味受体的生物学特征、信号转导机制及苦味剂和苦味抑制剂对苦味受体的影响[J].动物营养学报,2017,29(3):769-775,7.
