高等学校化学学报2017，Vol.38Issue(8)：1347-1353,7.DOI:10.7503/cjcu20170047
虚拟分子印迹与表面增强拉曼散射联用技术用于孔雀石绿的超灵敏检测
Ultrasensitive Detection of Malachite Green Using the Coupling Technique of Dummy Molecular Imprinting and Surface-enhanced Raman Scattering
摘要
Abstract
The coupling technique of molecular imprinting with surface enhanced Raman scattering is regarded as a promising analysis method due to its properties of high sensitivity and selectivity.However, the traditional molecular imprinting technique is very difficult to thoroughly remove template molecules.So, the technique will result in strong background interference impacting the test results when it is combined with the surface-{enhanced} Raman scattering spectroscopy.In this study, the Ag particles were first synthesized adopting the method of ascorbic acid reduction.Then, the as-prepared Ag particles were silanized using 3-methacryloxypropyltrimethoxysilane.Finally, the dummy molecularly imprinted polymers were synthesized using abietic acid replacing malachite green as the template molecule to react with methacrylamide functional monomer.The {results} show that the resulting "core-shell" composite substrate has a more remarkable SERS enhancement than Ag substrate.And its detection limit for malachite green can down to 10-11 mol/L.This method can eliminate the background interference and improve the accuracy of the analysis results, which provide a new method for the ultrasensitive detection of organic dyes.关键词
虚拟分子印迹聚合物/表面增强拉曼散射/孔雀石绿/银粒子Key words
Dummy molecularly imprinted polymer/Surface-enhanced Raman scattering/Malachite green/Ag particles分类
化学化工引用本文复制引用
马芳晨,李欣,任晓慧..虚拟分子印迹与表面增强拉曼散射联用技术用于孔雀石绿的超灵敏检测[J].高等学校化学学报,2017,38(8):1347-1353,7.基金项目
国家自然科学基金(批准号: 51579057, 51379052)资助.Supported by the National Natural Science Foundation of China(Nos.51579057, 51379052). （批准号: 51579057, 51379052）
