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埃洛石纳米管在生物医学应用中的研究进展

马智 李英乾 丁彤 董俊杰 秦永宁

化工进展2017,Vol.36Issue(8):3032-3039,8.
化工进展2017,Vol.36Issue(8):3032-3039,8.DOI:10.16085/j.issn.1000-6613.2016-2296

埃洛石纳米管在生物医学应用中的研究进展

Research progress of halloysite nanotubes in biomedical science application

马智 1李英乾 1丁彤 1董俊杰 1秦永宁1

作者信息

  • 1. 天津大学化工学院,天津市应用催化科学与工程重点实验室,天津300072
  • 折叠

摘要

Abstract

Halloysite nanotube (HNTs) is a new natural aluminosilicate nanometer material.It has many advantages,such as unique nano-tubular structure,high specific surface area,and high reactivity.In recent years,HNTs has had more and more important applications in the field of biomedical transport.In this paper,the structure and properties of HNTs were briefly introduced.The feasibility of HNTs application in biomedical field was analyzed.The researches and applications of HNTs in enzyme immobilization,biological imaging,biological scaffold,targeted transport of cytotoxic drugs and gene,and other aspects of the application,were illustrated emphatically.Compared with traditional inorganic nanomaterials,HNTs has many advantages in the field of biomedical applications such as good immobilization effect,easy chemical modification,high biocompatibility,low toxicity,and high selectivity.Finally,the challenges of the HNTs in the field of biomedicine were pointed out,including long medical results conversion cycle,high medical costs,and unexplained drug release mechanism.The prospects of the HNTs in a series of modem medical technologies,such as disease diagnosis,targeted delivery of drugs and follow-up treatment,were also discussed.

关键词

埃洛石纳米管/载体/酶固定化/药物/基因靶向传递/生物成像

Key words

halloysite/support/enzyme immobilization/drug/gene targeting delivery/biological imaging

分类

化学化工

引用本文复制引用

马智,李英乾,丁彤,董俊杰,秦永宁..埃洛石纳米管在生物医学应用中的研究进展[J].化工进展,2017,36(8):3032-3039,8.

化工进展

OA北大核心CSCDCSTPCD

1000-6613

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