内科理论与实践2017，Vol.12Issue(3)：176-179,4.DOI:10.16138/j.1673-6087.2017.03.007
胃静脉曲张黏合剂治疗对门脉高压性胃病的影响
The study of effect on portal hypertensive gastropathy after treating gastric varices by endoscopic injection of tissue adhesive
摘要
Abstract
Objective To investigate the effect on portal hypertensive gastropathy (PHG) after treating the gastric varices by endoscopic injection of tissue adhesive.Methods Decompensated hepatitis B cirrhosis patients with gastric varices or isolated gastric varices from January 2013 to August 2015 were enrolled.The improved "sandwich" therapy with sclerosant+tissue adhesive+sclerosant was administrated.Patients were followed up at 3-month,6-month,and 1 year after treatment.The clinical efficacy of the endoscopy treatment and the change of incidence in PHG were observed.Results There were 171 patients received endoscopic sclerotherapy for 242 times.At 6-month and 12-month of follow up,the effective rates were 98.8％ (169 cases) and 88.9％ (152 cases),respectively.The survival rate at 12-month follow up was 98.2％(168 cases).Before treatments,the incidence of PHG were 35.5％,at 3-month of follow up was 38.1％,the difference was not significant (P＞0.05);the incidence of PHG was 48.0％ at 6-month and 84.2％ at 1-year of follow up,the differences were statistically significant.Conclusions The endoscopic injection of tissue adhesive to patients with gastric varices can decrease the death rate in acnte hemorrhage and increase the survival.However,with the passage of time,the incidence of PHG increased obviously.For improving the life quality and survival of patients with PHG,multiple combination therapies to decrease the incidence of PHG is needed.关键词
胃静脉曲张/黏合剂治疗/门脉高压性胃病Key words
Gastric varices/Treatment with tissue adhesive/Portal hypertensive gastropathy分类
医药卫生引用本文复制引用
施建平,张毅,顾昊,陈莺,曹佳,瞿春莹,沈峰,周敏,徐雷鸣..胃静脉曲张黏合剂治疗对门脉高压性胃病的影响[J].内科理论与实践,2017,12(3):176-179,4.基金项目
上海市市级医院适宜技术项目(项目编号:SHDC12014220) （项目编号:SHDC12014220）
浦东新区卫生系统重点学科建设项目(项目编号:PWZx2014-07) （项目编号:PWZx2014-07）
