青岛大学医学院学报2017，Vol.53Issue(3)：272-275,4.DOI:10.13361/j.qdyxy.201703006
单体素磁共振波谱在无病灶颞叶癫痫诊断中的应用
VALUE OF SINGLE-VOXEL MAGNETIC RESONANCE SPECTROSCOPY IN THE DIAGNOSIS OF TEMPORAL LOBE EPILEPSY WITHOUT LESIONS IN CONVENTIONAL MRI
左晨晨 1李伟 2张丕宁 1宋双双 1段崇锋 1隋庆兰1
作者信息
- 1. 青岛大学附属医院放射科,山东青岛 266500
- 2. 莱阳市中心医院放射科
- 折叠
摘要
Abstract
Objective To investigate the role and value of single-voxel magnetic resonance spectroscopy (1H-MRS) in diagnosing patients with temporal lobe epilepsy without lesions in conventional magnetic resonance imaging (MRI).Methods A total of 33 patients with temporal lobe epilepsy and 12 age-and sex-matched healthy subjects were enrolled in the study.1H-MRS was performed in the ipsilateral and contralateral epileptogenic zones of patients and the hippocampus region of healthy subjects.The ratios of N acetylaspartate (NAA)/creatine (Cr),choline (Cho)/Cr,and NAA/(Cr+Cho) were determined.Results The ratios of NAA/(Cr+Cho) and NAA/Cr in the ipsilateral epileptogenic zone of patients were lowest,followed by the contralateral epileptogenic zone of patients,and the hippocampus region of healthy subjects,and the differences were statistically significant (F=15.655,13.033;P＜0.01).Conclusion 1 H-MRS has a certain value in the diagnosis of temporal lobe epilepsy by displaying the changes in NAA/Cr and NAA/(Cr+Cho).关键词
癫痫,颞叶/磁共振波谱学/单体素/诊断显像Key words
epilepsy, temporal lobe/magnetic resonance spectroscopy/single voxel/diagnostic imaging分类
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左晨晨,李伟,张丕宁,宋双双,段崇锋,隋庆兰..单体素磁共振波谱在无病灶颞叶癫痫诊断中的应用[J].青岛大学医学院学报,2017,53(3):272-275,4.
